CJC-1295
CJC-1295 without DAC (also called Mod GRF 1-29) is a lab-made peptide of 29 amino acids, based on the first part of a natural hormone called GHRH, with four building blocks swapped for sturdier ones.
Where it came from
CJC-1295 was developed by ConjuChem Biotechnologies in Montreal and first described in 2005 by Lucie Jette and colleagues in the journal Endocrinology.
The version without DAC, also called Mod GRF 1-29, is the same 29-amino-acid chain without ConjuChem's add-on.
Worth knowing
- Mod GRF 1-29 differs from the natural hormone piece it copies at four spots. Each swap fixes a known weak point where enzymes cut the chain or oxygen damages it.
- DAC stands for Drug Affinity Complex: a chemical hook added to one end, designed to latch onto albumin, the most common protein in blood.
- Strictly speaking, "CJC-1295 without DAC" is a misnomer, since CJC-1295 was defined as the version with DAC. The older name for the chain on its own is tetrasubstituted GRF(1-29), meaning GRF(1-29) with four swaps.
At a glance
| Detail | Value |
|---|---|
| Chain length | 29 amino acids |
| Chemical formula | C152H252N44O42 |
| Weight of one molecule | 3367.9 g/mol |
| Form | Freeze-dried powder |
| Storage | Sealed in a freezer at -20 °C, away from light |
Weight is shown in grams per mole (g/mol), the standard unit chemists use. It's the number a lab checks a sample against to confirm it's the right compound.
Lab reports
Every batch (called a lot) of CJC-1295 is tested by an independent lab. The report shows the lab, the test date, the lot number, how pure the sample is and how much is in the vial. Find them on the Certificates of Analysis page. New to lab reports? Start with How to read a peptide lab report.
The weight above is for the compound on its own. A report may show a slightly higher figure, because the powder also carries a little salt left from manufacturing. Peptide salt forms explains why.
Storage
Keep the vial sealed in a freezer at -20 °C, away from light, and let it warm to room temperature before opening so moisture doesn't get in. More in Storing lyophilized (freeze-dried) peptides in the lab and the Research handling guidelines.
For research use only. Not for human or veterinary use.